Muscle Building 2 mg/vial Peptides Body Protection Pentadecapeptide
Bpc157 CAS 137525-51-0 Weight Loss Steroid Bpc157
BPC 157 (Body Protection Compound-157) is a pentadecapeptide made
up of 15 amino acids. The amino acids sequence in BPC 157 is
similar to a portion of the human BPC amino acid sequence. Human
BPC is found in the gastric juice. Experiments have shown that BPC
157 enhances the healing of wounds, including tendons wounds such
as transected Achilles tendons of rats. The aim of this study was
to investigate the probable mechanism that BPC 157 utilizes to
accelerate the healing process in an injured tendon.
The study used two group of tendon explants of which one group was
cultured in a BPC 157-containing medium while the other group was
cultured in a medium lacking BPC 157. These cultures were
thereafter examined for tendon fibroblasts outgrowths. Such
outgrowths indicated tendon regeneration.The results revealed that
the explants' outgrowth was significantly accelerated in the
culture containing BPC 157 as compared to the culture lacking BPC
Also, a MTT assay did show that BPC 157 does not directly affect
cellular proliferation in a culture of rat-derived Achilles tendon.
However, results also showed that BPC 157 significantly increased
the survival of cells under oxidative stress. Furthermore, the
Transwell filter migration assay showed that BPC 157 significantly
increased in-vitro fibroblast migration in a dose-dependent
fashion. Moreover, BPC 157 accelerated the dispersal of the
fibroblasts in culture dishes in a dose-dependent manner.
BPC 157 has a strong anti-inflammatory activity in both acute and
chronic inflammation models.In fact, preliminary results in
clinical trials suggest that BPC 157 may become an important
therapeutic tool for the treatment of inflammatory bowel
disease.BPC 157 was shown to accelerate wound healing and to have a
marked angiogenic effect.In addition, it significantly facilitates
the healing of bone fracture in rats.This peptide also exhibits an
osteogenic effect significantly improving the healing of segmental
bone defect.BPC 157 accelerates the healing of transected rat
Achilles tendon and transected rat quadriceps muscle.
Because BPC 157 has proven to be isolated from gastric juices, it
should not be a surprise to find that various scientific studies
that have been conducted on animal test subjects have been able to
pinpoint several links between the peptide's presence and digestive
tract functionality. Specifically, it has been determined that BPC
157 exhibits the capacity to regulate and control the manner in
which the digestive tract can operate.
One of the ways that BPC 157 accomplishes this is through
safeguarding the endothelium, which is the thin layer of cells that
line the blood vessels' interior surface. Another way the peptide
carries out regulatory function is by being a key factor in the
process of angiogenesis; that is, the process in which new blood
vessels are formed from pre-existing blood vessels.
This latter process is further bolstered by BPC 157's ability to
form granulation tissue; this term references the new connective
tissues and tiny blood vessels that develop on the surface of
wound, thus making the peptide an important piece to the overall
wound healing process. Further studies have also shown that the
peptide's inherent functionality allows it to contain
anti-inflammatory properties. Additionally, these studies have
determined that BPC 157 can also help in the regulation and control
of blood flow throughout an animal test subject's gastro-intestinal
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