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Categories | Mouse Monoclonal Antibody |
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Brand Name: | BT Lab |
Model Number: | BT-MCA0422 |
Certification: | CE,ISO9001:2005, MSDS |
Place of Origin: | Shanghai,China |
MOQ: | Negotiation |
Price: | Negotiation |
Payment Terms: | T/T, Western Union |
Supply Ability: | In Stock |
Delivery Time: | 2-7 business days |
Packaging Details: | Wrapped with ice pack and styrofoam package |
Reactivity: | human, mouse, rat |
Source: | mouse |
Mol wt: | 33 kDa |
Applications: | WB, ELISA |
Purity: | >98% |
Custom: | Available |
Company Info. |
Shanghai Korain Biotech Co., Ltd |
View Contact Details |
Product List |
Highly specific ING2 Rabbit Monoclonal Antibody
Cat.No. BT-MCA0422 Size: 20ul/50ul/100ul Datasheet Request
Product Information
Clonallity: Monoclonal
Applications: WB, ELISA
Source: mouse
Isotype: IgG
Protein Name: ING2
Immunogen: ING2 fusion protein
Calculated molecular weight: 33 kDa
Synonyms: ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2
Species specificity: human, mouse, rat
Recommended Dilution:
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at
-20oC. Store at 4°C for a month, for one year store at -20°C. When
reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody,
the antibody is stable for at least six weeks at 2-20°C. Avoid
repeated freeze/thaw cycles.
Background
ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. It is induced by the DNA-damaging agents etoposide and neocarzinostatin. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.
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