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Highly Specific Mouse Source ING2 Rabbit Protein Monoclonal Antibody

Categories Mouse Monoclonal Antibody
Brand Name: BT Lab
Model Number: BT-MCA0422
Certification: CE,ISO9001:2005, MSDS
Place of Origin: Shanghai,China
MOQ: Negotiation
Price: Negotiation
Payment Terms: T/T, Western Union
Supply Ability: In Stock
Delivery Time: 2-7 business days
Packaging Details: Wrapped with ice pack and styrofoam package
Reactivity: human, mouse, rat
Source: mouse
Mol wt: 33 kDa
Applications: WB, ELISA
Purity: >98%
Custom: Available
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Highly Specific Mouse Source ING2 Rabbit Protein Monoclonal Antibody

Highly specific ING2 Rabbit Monoclonal Antibody

Cat.No. BT-MCA0422 Size: 20ul/50ul/100ul Datasheet Request


Product Information

Clonallity: Monoclonal

Applications: WB, ELISA

Source: mouse

Isotype: IgG

Protein Name: ING2

Immunogen: ING2 fusion protein

Calculated molecular weight:​ 33 kDa

Synonyms: ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2

Species specificity: human, mouse, rat

Recommended Dilution:

WB : 1:1000-1:6000

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.


Background

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. It is induced by the DNA-damaging agents etoposide and neocarzinostatin. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.


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